As of 11:20 a.m., the north left shoulder, left lane and right lane are closed.
Traffic is backed up for about 5 miles.
A tractor-trailer crash has closed all northbound lanes of I-81 in Botetourt County, according to VDOT.
Authorities say the crash happened near mile marker 159.9.
As of 9:28 a.m., drivers should expect delays.
Stay with 10 News as this breaking news story develops.
Source: WSLS News 10